Research

The Amish and Plain communities provide an optimal population to unravel genetic causes and modifiers of rare inherited disorders and more common complex diseases. The CHC’s research program is integrated into our clinical services and is instrumental in advancing medical knowledge. It serves as a model resource for medical and scientific researchers worldwide.

Poster Presentations

A few members of the CHC Board of Directors presented information about the CHC at two genetics meetings in the Spring of 2012. They presented information about the effect of genetic disorders on the local community. See the posters below.

American College of Medical Genetics and Genomics 2012 Annual Clinical Genetics Meeting
Poster
: “An innovative approach to overcome healthcare disparities in the Indiana Plain Communities”

Society for Inherited Metabolic Disorders 2012 Annual Meeting
Poster
: “Untapped potential: An initial assessment of the prevalence of inborn
errors of metabolism in the Indiana Amish and Mennonite communities”

Bio-Resource Repository

The Bio-Resource Repository (BRR) is an integral component of the CHC and assists in the elucidation of genetic causes, contributors, and modifiers of a wide range of medical disorders while simultaneously addressing the specialized health concerns of the Amish community. DNA, serum, and plasma samples are stored for each patient who consents to participate. These samples are then made available for use in medical research to outside researchers.

Research Board

The CHC Research Board governs research sampling access and use and is comprised of individuals representing various fields and disciplines, including medicine, molecular genetics, epidemiology, medical ethics, and statistics.  Additionally, one Amish community representative with veto vote capabilities ensures community value alignment in the CHC research program.